This prohibition doubtless came early in the prophet’s life, for Hebrew youth generally married at an early age (see on Gen. 38:1; 2 Kings 22:1; 23:36; see Vol. II, p. 151). The reason for this prohibition is indicated in Jer. 16:3, 4. Both parents and children were soon to suffer the most tragic fate. Jeremiah’s unmarried state was thus a sign to that rebellious generation. Compare Isa. 8:18; Eze. 24:24, 27. The conduct of the work of God often requires personal sacrifices (Luke 14:26; see on 1 Cor. 7:29).