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2 Kings 19:22
Whom hast thou reproached and blasphemed? and against whom hast thou exalted thy voice, and lifted up thine eyes on high? even against the Holy One of Israel. (2 Kings 19:22)
The Holy One of Israel.
 This is a favorite phrase with Isaiah. He uses it 27 times in his book. It appears only five times in the rest of the Bible (Ps. 71:22; 78:41; 89:18; Jer. 50:29; 51:5).