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1 Timothy 4:5
For it is sanctified by the word of God and prayer. (1 Timothy 4:5)
Prayer.
 Genuine prayer reveals man’s attempt to cooperate fully with God’s plan for his restoration from sin. Prayer before each meal and frequently throughout the day is not too often to voice gratefulness for the love and wisdom of the Lord (see on Col. 3:17).
Word of God.
That is, by His express command. Christians set their pattern of living consistently with the Bible.
Sanctified.
 Gr. hagiazō, “to treat as holy” (see on John 17:17). God has ordained, or set apart, marriage (see on 1 Tim. 4:3). He has also set apart certain items appointed for use as food, and they are therefore “sanctified,” or set apart, each for its intended use.